Monoclonal antibodies

A new promising antibody with
approx. 15-fold improved anti-cancer effect.

CIBEX enables the production of antibodies (MAbs) which have a unique, fucose-free glycan pattern that leads to enhanced effector function.

Ciliates provide a unique and unusual glycan pattern
(e.g. CiMAb C2B8):

  • fucose-free

  • two-antenna core structure with up to 5 mannoses

  • terminal glucoses

Typical mammalian glycan pattern

(e.g. MabThera ®, only the most frequent forms are depicted)

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